Enhancing Ulcerative Colitis Care: Combining a Fasting Mimicking Diet with Induction Therapy

Authors

Umed Norkulov, University of Central FloridaFollow
Arianna Rivera, University of Central FloridaFollow
Fawaz Qazi, University of Central FloridaFollow

Streaming Media

Files

Course Code

HSC

Course Number

4930

Faculty/Instructor

Dr. Cheryl Cavaliere

Faculty/Instructor Email

Cheryl.Cavaliere@ucf.edu

About the Author

This project was made by Fawaz Qazi, Umed Norkulov, and Arianna Rivera, seniors majoring in Health Sciences. We would like to thank Dr. Cheryl Cavaliere for this opportunity to present at the Amy Zeh High-Impact Practices Course Designation Student Showcase.

We also wish to acknowledge the clinical teams and principal investigators behind the NCT04505410 trial for providing the essential research data. Their work in addressing Ulcerative Colitis has significantly contributed to both our project and the broader field of gastroenterology.

Abstract, Summary, or Creative Statement

This project analyzed a clinical trial investigating the effectiveness of adding a Fasting-Mimicking Diet (FMD) to advanced induction therapy for patients with Ulcerative Colitis (UC) The study (NCT0405410) was a Phase 3, randomized controlled trial involving 32 active participants. The intervention group (n=14) received advanced therapy plus the FMD, while the control group (n=18) received therapy alone. The primary objective was to determine if the FMD could improve remission rates and biomarkers. The trial found a statistically significant (P=0.05) benefit for the combined treatment group. The intervention group achieved a 57% clinical response rate compared to 38% in the control group. These results suggest that an FMD isa promising and safe adjunctive (supportive) therapy for managing UC.

Keywords

Ulcerative Colitis (UC), Fasting Mimicking Diet (FMD), Induction Therapy, Clinical Trials, Inflammatory Bowel Disease (IBD)

Recommended Citation

Norkulov, Umed; Rivera, Arianna; and Qazi, Fawaz, "Enhancing Ulcerative Colitis Care: Combining a Fasting Mimicking Diet with Induction Therapy" (2025). High Impact Practices Student Showcase Fall 2025. 39.
https://stars.library.ucf.edu/hip-2025fall/39