Abstract
Ginger (Zingiber Officinale) has been used in Asia for centuries to treat various ailments. Ginger has been reported to alleviate migraine pain via four bioactive compounds that can reduce nitric oxide synthase (NOS) resulting in the inhibition of nitric oxide (NO). The inhibition of nitric oxide results in the vasoconstriction of the intracranial blood vessels alleviating migraine pain. It is hypothesized that ginger has structural similarities to vasoconstrictor drugs causing similar receptor interactions. A review of the bioactive compounds in ginger and popular vasoconstrictor drugs was done to determine structural similarities. The results of this study show that the compounds in ginger share no structural similarities with vasoconstrictor drugs used in the treatment of migraine headaches.
Thesis Completion
2017
Semester
Fall
Thesis Chair/Advisor
Elsheimer, Seth
Co-Chair
Samsam, Mohtashem
Degree
Bachelor of Science (B.S.)
College
College of Sciences
Department
Chemistry
Degree Program
Biochemistry
Location
Orlando (Main) Campus
Language
English
Access Status
Open Access
Release Date
12-1-2017
Recommended Citation
Aleger, Nathan Vorbes, "Exploration of Bioactive Compounds of Ginger as a Folk Remedy for Migraines" (2017). Honors Undergraduate Theses. 251.
https://stars.library.ucf.edu/honorstheses/251