Abstract

The prevalence of herpes simplex virus (HSV) infection globally is high, and although there is no cure for it, the antiviral drug acyclovir is used to alleviate symptoms. There are two types of HSV: HSV-1, which typically infects the oral area, and HSV-2, which is associated with genital infections. A mother who carries the infection may transmit it to a neonate in different ways, most commonly via vaginal delivery in the presence of active lesions. There are three types of HSV disease that affect newborns: skin, eyes or mouth (SEM) disease, central nervous system (CNS) disease, or disseminated disease. The purpose of this study was to examine the long-term effects of the infection and the treatment used in neonates infected with HSV. Data collection consisted of original case reports published in Medline, CINHAL, and Google Scholar. Two case reports were found, and this narrative review compares the cases, which report recurrences and outcomes of HSV infection identified in the three databases. Both cases were consistent with recurrence of CNS disease, and one showed signs of a slight developmental delay that may have been related to the CNS insult.

Thesis Completion

2019

Semester

Fall

Thesis Chair/Advisor

Castillo, Humberto Lopez

Co-Chair

Rovito, Michael

Degree

Bachelor of Science (B.S.)

College

College of Health and Public Affairs

Department

Health Sciences

Degree Program

Health Sciences Pre-clinical

Language

English

Access Status

Open Access

Release Date

12-1-2019

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