Keywords
biomaterial, mechanical properties, biodegradability, magnesium composite, bone implant, biodegradable
Abstract
Magnesium composites have the potential to be used within the medical setting as a material, particularly for bone implants. Their potential comes from their possession of biodegradability characteristics and material properties that resemble the cortical bone. The biodegradability of the magnesium biomaterials can reduce the need for a second surgery to remove implants when a level of bone regeneration is reached to be self-sufficient, therefore removing the dependency on the implant. However, magnesium in its naturally occurring state demonstrates high corrosivity and degradation when simulated in a biological context. We investigate a magnesium composite (magnesium-bioglass) by testing biodegradation and mechanical properties, evaluating the differences in properties when compared to the mechanical properties of pure magnesium, and analyzing scanning electron microscopy results applied to samples immersed in a solution to simulate the in vivo setting. Through the various modes of fabrication of the magnesium composites, increased bioactivity can be measured. The results support the potential of using the bioactive magnesium-bioglass composites for orthopedic implants.
Thesis Completion Year
2024
Thesis Completion Semester
Spring
Thesis Chair
Razavi, Mehdi
College
College of Medicine
Department
College of Medicine
Thesis Discipline
Molecular Biology and Microbiology
Language
English
Access Status
Campus Access
Length of Campus Access
1 year
Campus Location
Orlando (Main) Campus
STARS Citation
Xie, Queenly, "Biodegradability and Mechanical Properties of Bioresorbable Magnesium Composites for Bone Implants" (2024). Honors Undergraduate Theses. 131.
https://stars.library.ucf.edu/hut2024/131