Keywords

biomaterial, mechanical properties, biodegradability, magnesium composite, bone implant, biodegradable

Abstract

Magnesium composites have the potential to be used within the medical setting as a material, particularly for bone implants. Their potential comes from their possession of biodegradability characteristics and material properties that resemble the cortical bone. The biodegradability of the magnesium biomaterials can reduce the need for a second surgery to remove implants when a level of bone regeneration is reached to be self-sufficient, therefore removing the dependency on the implant. However, magnesium in its naturally occurring state demonstrates high corrosivity and degradation when simulated in a biological context. We investigate a magnesium composite (magnesium-bioglass) by testing biodegradation and mechanical properties, evaluating the differences in properties when compared to the mechanical properties of pure magnesium, and analyzing scanning electron microscopy results applied to samples immersed in a solution to simulate the in vivo setting. Through the various modes of fabrication of the magnesium composites, increased bioactivity can be measured. The results support the potential of using the bioactive magnesium-bioglass composites for orthopedic implants.

Thesis Completion Year

2024

Thesis Completion Semester

Spring

Thesis Chair

Razavi, Mehdi

College

College of Medicine

Department

College of Medicine

Thesis Discipline

Molecular Biology and Microbiology

Language

English

Access Status

Campus Access

Length of Campus Access

1 year

Campus Location

Orlando (Main) Campus

Available for download on Saturday, May 03, 2025

Share

COinS
 

Rights Statement

In Copyright