Abstract

The invention provides a composition comprising a plurality of nanoceria particles, a sufficient amount of at least one inhibitor of human carbonic anhydrase II associated with said plurality of nanoceria particles, and a pharmaceutically acceptable carrier containing said plurality of nanoceria particles with associated inhibitor. One preferred inhibitor of human carbonic anhydrase II comprises 4-carboxybenzene sulfonamide. The disclosed composition is useful in treatment of glaucoma.

Document Type

Patent

Patent Number

US 7,959,949

Application Serial Number

12/147,759

Issue Date

6-14-2011

Current Assignee

Joint Assignment w/UCFRF: North Dakota State University

Assignee at Issuance

Joint Assignment w/UCFRF: North Dakota State University

College

Advanced Materials Processing & Analysis Center (AMPAC)

Department

Advanced Materials Processing & Analysis Center (AMPAC)

Allowance Date

3-4-2011

Filing Date

6-27-2008

Assignee at Filing

Joint Assignment w/UCFRF: North Dakota State University

Filing Type

Nonprovisional Application Record

Donated

no

Share

COinS