Abstract
Disclosed is a composition immunologically targeted to Alzheimer’s disease (AD), the composition containing amine functionalized nanoparticles of Cerium oxide coated with polyethylene glycol and bearing an antibody specific for an amyloid-beta antigen associated with AD. The invention also includes a medication manufactured with the targeted nanoceria particles and methods of treatment by administering the targeted nanoceria particles to patients in need thereof.
Document Type
Patent
Patent Number
US 8,877,207 B2
Application Serial Number
13/184,660
Issue Date
11-4-2014
Current Assignee
Joint Assignment w/UCFRF: University of L'Aquila
College
NanoScience Technology Center
Department
NanoScience Technology Center
Allowance Date
9-4-2014
Filing Date
7-18-2011
Assignee at Filing
NanoScience Technology Center
Filing Type
Nonprovisional Application Record
Donated
no
Recommended Citation
Seal, Sudipta; Cimini, Annamaria; D'Angelo, Barbara; and Das, Soumen, "Nanoparticles of Cerium Oxide Targeted to an Amyloid-Beta Antigen of Alzheimer's Disease and Associated Methods" (2014). UCF Patents. 413.
https://stars.library.ucf.edu/patents/413