Synthesis and biological activity of a series of highly functionalized phenylamdes

Abstract

This report deals with the synthesis, characterization, and biological activity of a series of phenylamides possessing alkyl chains of varying length as well as additional alkyl amide moieties at the chain terminus. These compounds were targeted because of their expected activity against a specific fungus. The characterization and biological activity of many of the key intermediates are also reported. The biological activity of both the target compounds and the intermediates was determined by antibacterial and antifungal assays employing standard microbiological methodology. A total of thirty-two compounds were prepared and characterized; twenty-six of these were assayed. Several compounds displayed interesting activity in these screens.

Notes

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Graduation Date

1991

Semester

Summer

Advisor

Gupton, John T.

Degree

Master of Science (M.S.)

College

College of Arts and Sciences

Department

Chemistry

Format

PDF

Pages

203 p.

Language

English

Length of Campus-only Access

None

Access Status

Masters Thesis (Open Access)

Identifier

DP0028675

Subjects

Arts and Sciences -- Dissertations, Academic; Dissertations, Academic -- Arts and Sciences

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