Title

Patterning Polymerized Lipid Vesicles With Soft Lithography

Abstract

The applications of soft lithography in patterning polymerized lipid vesicles of 1,2-bis(tricosa-10,12-diynoyl)-s/i-glycero-3-phosphocholine on glass substrates are reported. We demonstrate that the polymerized vesicles can be used as a high molecular weight ink to be transferred from a PDMS stamp onto a glass substrate to form two-dimensional stripes with a controlled separation. By combining channel flow with dewetting within microfluidic networks, we assemble the polymerized vesicle into three-dimensional stripes and one-dimension lines on glass substrates. Atomic force microscopy shows that these patterned vesicle structures are stable on glass substrates. The simple, stable, and precise immobilization of lipid vesicles on solid substrates will open up the possibility of integrating them in biosensors and microelectronic devices. © 2005 American Chemical Society.

Publication Date

3-29-2005

Publication Title

Langmuir

Volume

21

Issue

7

Number of Pages

3132-3135

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1021/la0473153

Socpus ID

16244417496 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/16244417496

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