Title

Breakthrough In Chloroplast Genetic Engineering Of Agronomically Important Crops

Abstract

Chloroplast genetic engineering offers several unique advantages, including high-level transgene expression, multi-gene engineering in a single transformation event and transgene containment by maternal inheritance, as well as a lack of gene silencing, position and pleiotropic effects and undesirable foreign DNA. More than 40 transgenes have been stably integrated and expressed using the tobacco chloroplast genome to confer desired agronomic traits or express high levels of vaccine antigens and biopharmaceuticals. Despite such significant progress, this technology has not been extended to major crops. However, highly efficient soybean, carrot and cotton plastid transformation has recently been accomplished through somatic embryogenesis using species-specific chloroplast vectors. This review focuses on recent exciting developments in this field and offers directions for further research and development. © 2005 Elsevier Ltd. All rights reserved.

Publication Date

1-1-2005

Publication Title

Trends in Biotechnology

Volume

23

Issue

5

Number of Pages

238-245

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1016/j.tibtech.2005.03.008

Socpus ID

18144428771 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/18144428771

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