Title

Postmenopausal Females And The Link Between Oral Bisphosphonates And Osteonecrosis Of The Jaw: A Clinical Review

Keywords

Bisphosphonate-related osteonecrosis of the jaws; Oral bisphosphonates; Osteonecrosis of the jaw; Osteoporosis

Abstract

Purpose: To increase awareness for nurse practitioners (NPs) of new information concerning the plausible link between the oral bisphosphonate drug classification and necrosis in the jaw. Data sources: Selected research and clinical articles. In addition, several peer-reviewed, refereed medical and dental journals were consulted. Conclusions: Oral bisphosphonates are commonly prescribed by NPs for postmenopausal females with the diagnosis of osteoporosis to arrest bone loss and preserve bone density. Recent reports have shown a link between these medications and osteonecrosis of the jaw, which is a complication resulting in necrotic bone inside the mouth. Implications for practice: NPs must be able to determine early warning signs of osteonecrosis to ensure prompt referral to a dental specialist in order to prevent irreversible sequelae. Because of the aging population, osteoporosis is predicted to increase; therefore, treatment with these drugs and the side effects that go along with them will most likely also increase. © 2010 The Author(s) Journal compilation © 2010 American Academy of Nurse Practitioners.

Publication Date

10-1-2010

Publication Title

Journal of the American Academy of Nurse Practitioners

Volume

22

Issue

10

Number of Pages

534-539

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1111/j.1745-7599.2010.00549.x

Socpus ID

78650463998 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/78650463998

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