Title

Folding Of 16S Rrna In A Signal-Producing Structure For The Detection Of Bacteria

Keywords

16S rRNA; binary deoxyribozyme; detection of bacteria; DNA origami; fluorescent sensors

Abstract

Sixty-four DNA strands hybridize to 16S rRNA to form 32 deoxyribozyme catalytic cores that produce a fluorescent signal. The approach allows detection of 0.6 pM 16S rRNA, or about 3×104 bacterial cells in a PCR-free format. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Publication Date

9-27-2013

Publication Title

Angewandte Chemie - International Edition

Volume

52

Issue

40

Number of Pages

10586-10588

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1002/anie.201303919

Socpus ID

84884851846 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84884851846

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