Title

Influence Of Chain Lengths Of Liquid Crystals On Cholic Acid Detection

Keywords

And liquid crystal films; Cholic acid; Detection; Surfactants

Abstract

The concentration level of bile acids is a useful indicator for the diagnosis of liver diseases since individual suffering from liver diseases often has a sharp increase in bile acid concentration. Here we present a sensor platform based on the anchoring transition of nematic liquid crystal (LC), 4', 4-alkylcyanobiphenyls (nCB, n=5-8), at the surfactant-laden LC/aqueous interfaces for the detection of cholic acid (CA) in aqueous solution. In the sensor platform, the competitive adsorption of CA at the surfactant-laden LC/aqueous interface triggers a homeotropic-to-planar anchoring transition of the LC at the interface. We find the detection limit, which is the minimum concentration of CA required to trigger the LC transition, increases with the increase of the chain length of nCB. © 2013 SPIE.

Publication Date

11-4-2013

Publication Title

Proceedings of SPIE - The International Society for Optical Engineering

Volume

8828

Number of Pages

-

Document Type

Article; Proceedings Paper

Personal Identifier

scopus

DOI Link

https://doi.org/10.1117/12.2032202

Socpus ID

84886697233 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84886697233

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