Title

Tyrosine Nitration As Mediator Of Cell Death.

Abstract

Nitrotyrosine is used as a marker for the production of peroxynitrite and other reactive nitrogen species. For over 20 years the presence of nitrotyrosine was associated with cell death in multiple pathologies. Filling the gap between correlation and causality has proven to be a difficult task. Here, we discuss the evidence supporting tyrosine nitration as a specific posttranslational modification participating in the induction of cell death signaling pathways.

Publication Date

1-1-2014

Publication Title

Cellular and molecular life sciences : CMLS

Volume

71

Issue

20

Number of Pages

3939-3950

Document Type

Review

Personal Identifier

scopus

DOI Link

https://doi.org/10.1007/s00018-014-1662-8

Socpus ID

84909994370 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84909994370

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