A Highly Selective Fluorescence Turn-On Sensor For Extracellular Calcium Ion Detection

Keywords

calcium; cell imaging; extracellular calcium detection; fluorescence microscopy; fluorescence sensors

Abstract

A highly water-soluble, fluorescence turn-on sensor for Ca2+is reported. The sensor affords high selectivity in sensing Ca2+over other biologically important metal cations. The dissociation constant of the sensor in binding Ca2+is 0.92 mm. Fluorescence microscopy experiments demonstrate that the sensor is cell-impermeable and capable of detecting extracellular Ca2+.

Publication Date

7-18-2016

Publication Title

Chemistry - A European Journal

Volume

22

Issue

30

Number of Pages

10351-10354

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1002/chem.201602162

Socpus ID

84977117669 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84977117669

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