Liquid Crystal Droplet-Embedded Biopolymer Hydrogel Sheets For Biosensor Applications

Keywords

bile acids; biopolymers; hydrogel sheets; liquid crystals; sensors

Abstract

The development of simple, portable, and low-cost biosensing platforms is of great interest in the clinical diagnosis of disease. Here, we report liquid crystal (LC) droplet-embedded chitosan (CHI) hydrogel films formed by the Ag+ ion-triggered fast gelation of the CHI/surfactant complex-stabilized LC emulsion which is cast on substrates. The small sheets cut from the LC droplet-embedded hydrogel films combine the advantages of both hydrogels and LC droplets, offering a portable and label-free sensing platform for the real-time detection of bile acids in a small amount of solution. We find that the response time and detection limit of LC droplet-embedded hydrogel sheets for bile acids depend on their chemical structures.

Publication Date

2-24-2016

Publication Title

ACS Applied Materials and Interfaces

Volume

8

Issue

6

Number of Pages

3928-3932

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1021/acsami.5b11076

Socpus ID

84959020315 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84959020315

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