Epididymal Cystadenomas In Von Hippel-Lindau Disease Showing Increased Activity On ⁶⁸Ga Dotatate Pet/Ct

Creator

Georgios Z. Papadakis, NIH Clinical Center (CC)
Corina Millo, RADIS
Samira M. Sadowski, National Cancer Institute (NCI)
Ulas Bagci, University of Central Florida
Nicholas J. Patronas, NIH Clinical Center (CC)

Keywords

68 Ga DOTATATE PET/CT; Cystadenomas; Epididymal; Somatostatin receptors imaging; Von Hippel-Lindau (VHL) disease

Abstract

von Hippel-Lindau (VHL) disease is a familial cancer syndrome characterized by the development of a variety of malignant and benign tumors, including epididymal cystadenomas. We report a case of a VHL patient with bilateral epididymal cystadenomas who was evaluated with 68Ga DOTATATE PET/CT, showing intensely increased activity (SUVmax, 21.6) associated with the epididymal cystadenomas, indicating cell-surface overexpression of somatostatin receptors. The presented case supports the usefulness of somatostatin receptor imaging using 68Ga DOTA-conjugated peptides for detection and follow-up of VHL manifestations, as well as surveillance of asymptomatic gene carriers.

Publication Date

7-23-2016

Publication Title

Clinical Nuclear Medicine

Volume

41

Issue

10

Number of Pages

781-782

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1097/RLU.0000000000001314

Copyright Status

Unknown

Socpus ID

84979656445 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84979656445

STARS Citation

Papadakis, Georgios Z.; Millo, Corina; Sadowski, Samira M.; Bagci, Ulas; and Patronas, Nicholas J., "Epididymal Cystadenomas In Von Hippel-Lindau Disease Showing Increased Activity On ⁶⁸Ga Dotatate Pet/Ct" (2016). Scopus Export 2015-2019. 3600.
https://stars.library.ucf.edu/scopus2015/3600