Endolymphatic Sac Tumor Showing Increased Activity On ⁶⁸Ga Dotatate Pet/Ct

Creator

Georgios Z. Papadakis, NIH Clinical Center (CC)
Corina Millo, RAD and IS
Samira M. Sadowski, National Cancer Institute (NCI)
Ulas Bagci, University of Central Florida
Nicholas J. Patronas, NIH Clinical Center (CC)

Keywords

68 Ga-DOTATATE PET/CT; Endolymphatic sac tumors; Somatostatin receptors-imaging; Von Hippel-Lindau disease

Abstract

Endolymphatic sac tumors (ELSTs) are rare tumors arising from the epithelium of the endolymphatic sac and duct that can be either sporadic or associated with von Hippel-Lindau (VHL) disease. We report a case of a VHL patient with histologically proven residual ELST who underwent 68Ga DOTATATE PET/CT showing increased activity (SUVmax, 6.29) by the ELST. The presented case of a VHL-associated ELST with increased 68Ga DOTATATE uptake indicates cell-surface expression of somatostatin receptors by this tumor, suggesting the potential application of somatostatin receptor imaging using 68Ga DOTA-conjugated peptides in the workup and management of these patients.

Publication Date

7-23-2016

Publication Title

Clinical Nuclear Medicine

Volume

41

Issue

10

Number of Pages

783-784

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1097/RLU.0000000000001315

Copyright Status

Unknown

Socpus ID

84979703523 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84979703523

STARS Citation

Papadakis, Georgios Z.; Millo, Corina; Sadowski, Samira M.; Bagci, Ulas; and Patronas, Nicholas J., "Endolymphatic Sac Tumor Showing Increased Activity On ⁶⁸Ga Dotatate Pet/Ct" (2016). Scopus Export 2015-2019. 3604.
https://stars.library.ucf.edu/scopus2015/3604