18F-Fdg And 68Ga-Dotatate Pet/Ct In Von Hippel-Lindau Disease-Associated Retinal Hemangioblastoma

Abstract

Retinal hemangioblastomas are highly vascular benign tumors that can be encountered either sporadically or within the von Hippel-Lindau (VHL) syndrome. We report a case of a VHL patient with retinal hemangioblastoma who underwent PET/CT scans using F-FDG and Ga-DOTATATE. The tumor showed low-level F-FDG and increased Ga-DOTATATE activity, suggesting cell-surface overexpression of somatostatin receptors. The presented case indicates the clinical applications of somatostatin receptor imaging with Ga-DOTA-conjugated peptides in detection and follow-up of VHL manifestations, screening of asymptomatic gene carriers, and in diagnosis of sporadic retinal hemangioblastomas, which may have similar features on MRI with other retinal tumors.

Publication Date

3-1-2017

Publication Title

Clinical nuclear medicine

Volume

42

Issue

3

Number of Pages

189-190

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1097/RLU.0000000000001511

Socpus ID

85028254527 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85028254527

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