Avascular Necrosis Of The Hips With Increased Activity On 68Ga-Dotatate Pet/Ct

Abstract

Prolonged exposure to cortisol is one of the major causes of avascular bone necrosis (AVN). We report on a case of a woman with Cushing syndrome attributed to ectopic adrenocorticotropic hormone-secreting tumor who was evaluated with whole-body PET/CT study using Ga-DOTATATE. The scan showed increased activity by both femoral heads, corresponding to the margins of bilateral AVN seen on MRI. The presented data suggests AVN-induced reactive inflammatory alterations adjacent to the necrotic segment of the bone, which can be effectively targeted using radiolabeled somatostatin (SST) analogs.

Publication Date

3-1-2017

Publication Title

Clinical nuclear medicine

Volume

42

Issue

3

Number of Pages

214-215

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1097/RLU.0000000000001513

Socpus ID

85028240024 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85028240024

This document is currently not available here.

Share

COinS