Therapeutic Application Of Adult Stem Cells In The Heart

Keywords

Adult stem cells; Cardiovascular diseases; Progenitor cells

Abstract

Cell therapies have been explored as a potential treatment avenue to treat heart diseases, such as myocardial infarction, doxorubicin-induced cardiomyopathy, and heart failure. Embryonic and adult stem cells (ASCs) have been examined in animal and clinical settings. Unlike embryonic and induced pluripotent stem cells, ASCs do not pose a threat to form teratomas, nor do they have immune system concerns, making them ideal for therapeutic use in humans. In this review, we will investigate different characteristics and sources of adult stem cells and progenitor cells, as well as determine their efficacy in cell transplantation in experimental and clinical trials. In addition, we will propose other research avenues that may promote further understanding and use of ASCs in therapeutic designs.

Publication Date

1-1-2017

Publication Title

Methods in Molecular Biology

Volume

1553

Number of Pages

249-264

Document Type

Article; Book Chapter

Personal Identifier

scopus

DOI Link

https://doi.org/10.1007/978-1-4939-6756-8_20

Socpus ID

85013947028 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/85013947028

This document is currently not available here.

Share

COinS