Keywords
chemistry, DART, direct analysis real time
Abstract
Organic contamination on spaceflight hardware is an ongoing concern for spaceflight safety. In addition, for the goal of analyzing for possible evidence of extra-terrestrial life, it is necessary to consider the presence of terrestrial contamination. This paper will introduce and evaluate a new method using a direct analysis real time (DART) ionization source paired with a high resolution time of flight mass spectrometer (TOFMS) for the determination of organic contamination involved in spaceflight hardware and ground support materials. This novel analytical technique has significant advantages over current methodologies. Materials analyzed in this study were historically considered as probable contaminants in spaceflight related substrates. A user determined library was generated due to the non-traditional mass spectra generated by the DART. Continual improvement of analytical methods for the detection of trace levels of contaminants in potential drinking water sources is of extreme importance to both regulatory communities and concerned citizens. This paper will evaluate a novel analytical method using stir bar sorbtive (SBSE) extraction techniques combined with analysis with a DART TOFMS. Compounds of interest will include several representative pharmaceutical contaminants of emerging concern listed in EPA method 1694. Optimal SBSE and DART experimental parameters will be investigated along with accuracy, precision, limits of detection and calibration linearity.
Notes
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Graduation Date
2009
Advisor
Clausen, Christian
Degree
Doctor of Philosophy (Ph.D.)
College
College of Sciences
Department
Chemistry
Degree Program
Chemistry
Format
application/pdf
Identifier
CFE0002714
URL
http://purl.fcla.edu/fcla/etd/CFE0002714
Language
English
Release Date
March 2010
Length of Campus-only Access
None
Access Status
Doctoral Dissertation (Open Access)
STARS Citation
Loftin, Kathleen, "Development Of Novel Dart Tofms Analytical Techniques For The Identification Of Organic Contamination On Spaceflight-related Substrates And Aqueous Media" (2009). Electronic Theses and Dissertations. 3828.
https://stars.library.ucf.edu/etd/3828