Patient-specific model of lung deformation using spatially dependent constitutive parameters

    Authors

    O. J. Ilegbusi; B. Seyfi;R. Salvin

    Comments

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    Abbreviated Journal Title

    Math. Comput. Model. Dyn. Syst.

    Keywords

    lung deformation; subject-specific lung property; heterogeneity; contact-impact analysis; finite element method; IMAGE REGISTRATION; TECHNICAL NOTE; TISSUE; Computer Science, Interdisciplinary Applications; Mathematics, Applied

    Abstract

    Breathing-induced spatially dependent lung deformation is predicted using patient-specific elastic properties with the contact-impact analysis model. The lung geometry is derived from 4D CT scan data of real patients. The spatially varying Young's modulus for the patient is obtained from a previous study that used inverse deformation of the lung. The compact-impact analysis is implemented using the finite element method. The predicted lung deformation is compared with the results based on linear elasticity. The results are consistent with physiology, indicating large deformations near the diaphragm and smaller values at remote locations on the lobe. The effect of non-linearity of elastic property is most significant at the remote locations where the diaphragm-induced deformation is significantly attenuated.

    Journal Title

    Mathematical and Computer Modelling of Dynamical Systems

    Volume

    20

    Issue/Number

    6

    Publication Date

    1-1-2014

    Document Type

    Article

    Language

    English

    First Page

    546

    Last Page

    556

    WOS Identifier

    WOS:000340371800002

    ISSN

    1387-3954

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