Abstract
Conventional methods for diagnosis of human disease are, at times, limited in different regards including time requirement, either experimental or data processing, sensitivity, and selectivity. It is then that a Point of Care Criteria, which considers the true utility and usefulness of the device, is employed to propose new diagnostic devices capable of overcoming the aforementioned shortcomings of conventional tools. Nucleic acid, characterized for its predictable base-pairing nature, is considered to be a highly-selective, yet greatly modifiable device. Its behavior is then described through Boolean Logic, where “true” or “false” outputs are mathematically described as “1” and “0”, respectively. This mathematical approach is then referred to as Logic Gates, where outputs can be predicted based on satisfied environmental conditions. The mechanisms, capable of exhibiting Logic Gate behavior, are described.
Thesis Completion
2017
Semester
Fall
Thesis Chair/Advisor
Kolpashchikov, Dmitry
Degree
Bachelor of Science (B.S.)
College
College of Sciences
Department
Chemistry
Degree Program
Chemistry; Biochemistry Track
Location
Orlando (Main) Campus
Language
English
Access Status
Open Access
Release Date
12-1-2017
Recommended Citation
Blanco Martinez, Enrique J., "Literature Review on the Use of Nucleic Acid-Based Logic Gates for the Detection of Human Diseases" (2017). Honors Undergraduate Theses. 256.
https://stars.library.ucf.edu/honorstheses/256