Pharmacogenomic Management of Familial Hypercholesterolemia: An Integrative Review of the Literature
Abstract
The purpose of this thesis is to examine familial hypercholesterolemia (FH) and emerging pharmacogenomics therapies that propose to lower serum low density lipid (LDL) levels. The search of various data bases resulted in nine research articles being selected for review. Syntheses of the articles suggest emerging phamacogenomic drug therapy can improve treatment outcomes for individuals with a diagnosis of FH. The Human Genome Project (HGP) has had far reaching applications for genomic technologies and pharmacagenomic interventions, tailored to human conditions associated with select genomic traits. Synthesis of nine research articles demonstrate that little is known on the topic and reveals extensive gaps in the evidence. This thesis concludes with implications for nursing education, practice, policy and research along with limitations are noted.
Thesis Completion
2016
Semester
Summer
Thesis Chair/Advisor
Bushy, Angeline
Co-Chair
D'Amato-Kubiet, Leslee
Degree
Bachelor of Science in Nursing (B.S.N.)
College
College of Nursing
Location
UCF Daytona Beach
Language
English
Access Status
Open Access
Release Date
August 2016
Recommended Citation
Skibo, Brian V., "Pharmacogenomic Management of Familial Hypercholesterolemia: An Integrative Review of the Literature" (2016). Honors Undergraduate Theses. 76.
https://stars.library.ucf.edu/honorstheses/76
Included in
Genetic Phenomena Commons, Genetic Processes Commons, Medical Specialties Commons, Nursing Commons, Pharmacy and Pharmaceutical Sciences Commons