Title

A Comparative Analysis Of Two Different Sets Of Y-Chromosome Short Tandem Repeats (Y-Strs) On A Common Population Panel

Keywords

Forensic science; Microsatellites; Short tandem repeats; Y-chromosome; Y-STR

Abstract

A comparative analysis of two Y-STR loci sets was conducted on a population sample of 224 individuals, 114 Caucasians and 110 African Americans. One set of loci, designated the OSU 10-locus set, comprises variable, single copy, male-specific loci that are dispersed across the Y-chromosome. Parallel evaluations were performed using the 10 Y-chromosome loci most frequently used for forensic analysis, the loci chosen as the SWGDAM Y-STR loci. The OSU 10-locus set had a greater average number of alleles per locus and higher average gene diversity than the SWGDAM loci. The OSU 10-locus set found 220 unique haplotypes in 224 individuals. In ∼6000 pairwise haplotype comparisons for each population with each set of loci, the OSU 10-locus set also yielded a greater average number of allelic differences per pair than the SWGDAM loci. Finally, the overall linkage disequilibrium levels were lower for the OSU 10-locus set in the Caucasian population. In general, the OSU 10-locus set revealed a higher power of discrimination than the SWGDAM set. © 2009 Elsevier Ireland Ltd. All rights reserved.

Publication Date

1-1-2009

Publication Title

Forensic Science International: Genetics

Volume

4

Issue

1

Number of Pages

11-20

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1016/j.fsigen.2009.03.004

Socpus ID

70649104821 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/70649104821

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