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Theses/Dissertations from 2018

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Regulation of Extra-Pituitary Prolactin in Monocytes and Macrophages, Richard Barrett

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Knowledge and Attitudes Regarding the Recent Zika Outbreak Among a Sample of South Florida Residents, Mohamed Elakkari

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Dissecting the Components of Neuropathic Pain, Dale George

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Embryonic Stem Cell Derived Exosomes Enhance Cardiac Stem Cell Differentiation into Heart Cells, Jamillah Hammond

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Role of Mycobacterium avium paratuberculosis (MAP) and TNFSF15 SNPs on TL1A in CD, Sayf Al-Deen Hassouneh

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Development of a Non-Human Primate Model for Staphylococcus aureus Nasal Carriage, Amanda Lasseter

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Deciphering the Role of Adrenergic Hormones in Embryonic Cardiac Calcium Signaling and Metabolism, Jessica Peoples

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Role of Lipid Peroxide Derived Dicarboxylic Acids in Atherosclerotic Calcification, Aladdin Riad

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Characterization of Neural Cells Derived from Reelin-deficient Schizophrenic Patient iPS Cells, Nicole Roberts

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Neuromuscular Junction Defects in a Mouse Model of Charcot-Marie-Tooth Disease Type 2O, Thywill Sabblah

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PG-VTV Biogenesis Requires ATP to Facilitate Phosphorylation of Syntaxin 17, Anika Saxena

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Role of Single Nucleotide Polymorphisms (SNPs) in PTPN2/22 and Mycobacterium Avium Subspecies Paratuberculosis (MAP) in Rheumatoid Arthritis and Crohn's Disease, Robert Sharp

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Embryonic Stem Cell-Derived Exosomes Inhibit Doxorubicin-Induced Pyroptosis in Cell Culture Models, Zahra Tavakoli Dargani

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Exacerbation of ΔEFP Sickness in Escherichia coli By an Uncharacterized RNA Helicase, Robert Wingo

Theses/Dissertations from 2017

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Characterization of Novel Borrelia burgdorferi Transcripts Expressed during Tick and Mammalian Infection, Philip Adams

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A Major DNA Double Strand Repair Pathway and Cancer-Associated Circulating Proteins are Effecters of Epigenetic Revision., Brittany Allen

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Implication of Alpha-synuclein Transcriptional Regulation and Mutagenesis in the Pathogenesis of Sporadic Parkinson's Disease, Sambuddha Basu

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Development of Molecular Diagnostic Tools for Mycobacterium Species, Hillary Bengtson

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Chaperonin Containing TCP1 (CCT) as a Target for Cancer Therapy, Ana Carr

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Plasticity of Central and Peripheral Nervous System: Effects of Oxygen-Glucose Deprivation (OGD) and Chronic Intermittent Hypoxia (CIH), Jin Chen

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Targeted Therapy Development for Neurofibromatosis Type 2, Marisa Fuse

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Novel Cytokine Signaling and Molecular Therapeutic Strategy in Pancreatic Cancer, Sarah Gitto

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Consequences of Altered Short-Chain Carbon Metabolism in Heart Failure, Julie Horton

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Downregulation in IFNGR1 Increases Suspectiblity to Mycobacterium Avium Subspecies Paratuberculosis Infection in Crohn's Disease, Zin Mar Htun

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The Microbial Ecosystem of Beer Spoilage and Souring: Competition and Cooperation in the Age of Bioinformatics, Andrew Kettring

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Discovery and Characterization of Antimalarials with Novel Mechanisms of Action, Bracken Roberts

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Discovery and Characterization of Novel Antimicrobials against Mycobacterium tuberculosis, Carolina Rodrigues Felix

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The Actin-Severing Protein Cofilin Is Downstream Of Neuregulin Signaling, Is Regulated By The Tumor Suppressor Merlin, And Is Essential For Schwann Cell Myelination, Nicklaus Sparrow

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Cathepsin B Regulates VLDL Secretion Through LFABP Cleavage, Simeon Thibeaux

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A Chemical and Genetic Approach to Study the Polyamine Transport System in Drosophila, Minpei Wang

Theses/Dissertations from 2016

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Could Dietary Peroxidized Lipids provoke an Intestinal Inflammatory Response?, Mitsushita Doomra

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The mauC gene encodes a versatile signal sequence and redox protein that can be utilized in native and non-native protein expression and electron trnasfer systems, Brian Dow

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Pyroglutamylated amyloid beta peptides enhance non-fibrillogenic aggregation of the unmodified peptide, Gregory Goldblatt

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Apolipoprotein-AI Regulates Hepatic VLDL Secretion by Controlling Intracellular VLDL-Trafficking, Bhavesh Gurwani

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VO-OHpic Treatment Reduces Cardiac Remodeling in Doxorubicin-Induced Cardiomyopathy, Taylor Johnson

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The Role of SOD1 Acetylation in Neurodegeneration, Michael Kaliszewski

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The Role of Type-I Interferon in Limiting Spread and Killing of an Oncolytic RNA Virus in Prostate Cells, Kritika Kedarinath

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Role of Kruppel-like Factor 8 (KLF8) in Cancer and Cardiomyopathy, Satadru Lahiri

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Neurological profile of older ApoE-PON1 double knockout mice, Connie Mitra

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Role of KLF8-CXCR4 signaling in Breast Cancer Metastasis, Debarati Mukherjee

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Involvement of miRNAs in the Development of Androgen Independent Prostate Cancer, Richard Ottman

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Chlamydia trachomatis Transformants Show a Significant Reduction in Rates of Invasion upon Removal of Key Tarp Domains, Christopher Parrett

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Malondialdehyde (MDA) and Glutathione Peroxidase (GPx) are Elevated in Crohns Disease-Associated with Mycobacterium Avium Subspecies Paratuberculosis (MAP), Ahmad Qasem

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Structural and functional characterization of enzymes of a novel group of tryptophylquinone cofactor containing oxidases, Esha Sehanobish

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BMP-7 Inhibits p38 and JNK Pathways and Increases M2 Macrophage Differentiation to Reduce Atherosclerosis in Apolipoprotein E-/- Mice, Heidi Shoulders

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The development of motuporamine derivatives and an investigation into their biological properties, Kristen Skruber

Theses/Dissertations from 2015

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TIMP-1 Activates a Unique Cardiac Stem Cell Population, CD63+ve/C-KIT+ve, Thereby Enhancing Cardiac Differentiation, and Protects the Heart From Adverse Cardiac Remodeling Following Myocardial Infarction, Latifa Abdelli

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Differential Expression Of Proteins Involved In VLDL Trafficking Causes Reduced VLDL Secretion In Male Ames Dwarf Mice, Faisal Ahmed Moinuddin

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Diabetes Phenotypes in Transgenic Pancreatic Cancer Mouse Models, Toya Albury-Warren

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Evaluation of Intestinal Microbial Diversity and a New Antibiotic Regimen in Crohn's Disease Patients, Karel Alcedo

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The CT20 peptide as an agent for cancer treatment, Rania Bassiouni

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Synthesis and Characterization of Antimicrobial Non-Color Forming Silica-Silver Nanocomposite, Joshua Bazata

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Synthesis and Characterization of Core-Shell Zinc Silica Nanoparticles and Zinc Silica Nanogels for Agricultural Applications., Megan Berroth

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Development of human and rodent based in vitro systems toward better translation of bench to bedside in vivo results, Bonnie Berry

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A Binary Approach for Selective Recognition of Nucleic Acids and Proteins, Evan Cornett

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FMF assay for assessing vaccine generated antibodies in a biomimetic manner, Vipra Dhir

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Membrane topology of a broad-spectrum resistance factor responsible for lipid modification in Enterococcus faecium., Jesse Harrison

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Overexpression of human Cu/Zn Superoxide Dismutase in Mice; The Effect of Increase Superoxide Scavenging on Autonomic Control of the Heart., Jeffrey Hatcher

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Functional Identification of Nucleus Tractus Solitarius (NTS) Barosensitive Neurons: Effect of Chronic Intermittent Hypoxia (CIH), Jenya Kolpakova

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A high-content multiplexed screening platform for the evaluation and manipulation of force and fatigue of adult derived skeletal muscle myotubes in defined serum-free medium, Christopher McAleer

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The role of a highly conserved eubacterial ribosomal protein in translation quality control, Anusha Naganathan

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Genetically-programmed suicide of adrenergic cells in the mouse leads to severe left ventricular dysfunction, impaired weight gain, and symptoms of neurological dysfunction, Aaron Owji

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Development of Cytotoxic Natural Killer Cells for Ovarian Cancer Treatment, Veethika Pandey

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Proteomic Analysis Delineates the Signaling Networks of Plasmodium falciparum, Brittany Pease

Theses/Dissertations from 2014

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Preparation, Characterization, and Delivery of Antibodies Binding to a Model Oncogenic RNA, Human Initiator tRNA, Jennifer Archer

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Role of Cardiac Catecholamines in Embryos and Adults Under Stress, Candice Baker

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Modulation of cholera toxin structure and function by host proteins, Helen Burress

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The Anti-toxin Properties of Grape Seed Phenolic Compounds, Patrick Cherubin

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Amyotrophic Lateral Sclerosis: mechanism behind mutant SOD toxicity and improving current therapeutic strategies, Cassandra Dennys

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Cerium oxide Nanoparticles: Their Phosphatase Activity and its Control, Atul Dhall

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Genetic and biochemical characterization of the roles of two putative purine transporters in the infectious cycle of Borrelia burgdorferi, Sunny Jain

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In Vitro Characterization of Unmodified and Pyroglutamylated Alzheimer's Amyloid beta peptide, Jason Matos

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Host and Bacterial Determinants of Staphylococcus aureus Nasal Colonization in Humans, Gowrishankar Muthukrishnan

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Purification and Characterization of a Novel Selenocysteine Lyase from Enterococcus faecalis, Samantha Nelson

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The Role of LIM Kinase 1 and its Substrates in Cell Cycle Progression, Lisa Ritchey

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Validation Of A Novel Hypothesis Of Generating Foam Cells By Its Use To Study Reverse Cholesterol Transport, Bhaswati Sengupta

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Establishment of Methods for Isolation of Pnmt+ Cardiac Progenitor Cells, Namita Varudkar

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Antimicrobial Peptide Resistance and Immunomodulation by HIV-1 gp41, Matthew Wood

Theses/Dissertations from 2013

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The Role Of Mitochondrial Omi/htra2 Protease In Protein Quality Control And Mitophagy, Camilla Ambivero

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The Cytopathic Activity Of Cholera Toxin Requires A Threshold Quantity Of Cytosolic Toxin., Carly Bader

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Delineating Key Genetic Components On Linear Plasmid 36 That Contribute To Its Essential Role In Borrelia Burgdorferi Mammalian Infectivity., Tisha Choudhury

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Characterization Of Innate Immunity In The Female Reproductive Tract For The Prevention Of Hiv Acquisition, Colleen Eade

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Target Validation For Neurofibromatosis Type 2 Therapeutics., Alejandra Guinart

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Is Breakdown Of Fatty Acid Peroxides Involved In The Induction Of Apolipoprotein A1?, Rajat Gupta

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Immuno-pcr Detection Of Lyme Borreliosis, Micah Halpern

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Identification Of Epithelial Stromal Interaction 1 And Epidermal Growth Factor Receptor As Novel Kruppel-like Factor 8 Targets In Promoting Breast Cancer Progression, Tianshu Li

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The Contribution Of Visceral Fat To Positive Insulin Signaling In Ames Dwarf Mice, Vinal Menon

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Characterization Of Motility Alterations Caused By The Impairment Of Dynein/dynactin Motor Protein Complex, Swaran Nandini

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Role Of Host Immune Response And Bacterial Autolysin Atl In Human Nasal Colonization By Staphylococcus Aureus, Vanathy Paramanandam

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Molecular Regulators Of Post-golgi Vldl Transport Vesicle (pg-vtv) Biogenesis, Aladdin Riad

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Bone Morphogenetic Protein-7 (bmp-7) Polarizes Monocytes Into M2 Macrophages, Crystal Rocher

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Screening Of Quantum Dots For Toxicity On The Growth And Viability Of Escherichia Coli, Jeremy Tharkur

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Identification Of Proteins Regulating Vldl Sorting Into The Vldl Transport Vesicle (vtv) And Involved In The Biogenesis Of The Vtv, Samata Tiwari

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Cerium Oxide Nanoparticles Sensitize Pancreatic Cancer Cells To Radiation By Promoting Acidic Ph, Ros, And Jnk Dependent Apoptosis, Melissa Wason

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Mixed Valence Copper(cu)/silica Nanocomposite: Synthesis, Characterization And Systematic Antimicrobial Studies, Mikaeel Young

Theses/Dissertations from 2012

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The Dynamic Functions Of Bax Are Dependent On Key Structural And Regulatory Features, Rebecca Boohaker

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Light-activated Binary Nucleotide Reagent For Inactivation Of Dna Polymerase, Evan M. Cornett

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Cerium Oxide Nanoparticles Act As A Unique Catalyst And Scavenge Nitric Oxide And Peroxynitrite And Decrease Rns In Vitro And In Vivo, Janet Dowding

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Manipulation Of Host Signal Transduction Pathways And Cytoskeleton Functions By Invasive Bacterium Listeria Monocytogenes And Chlamydia Trachomatis, Shahanawaz Jiwani

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Amelioration Of Amyloid Burden In Advanced Human And Mouse Alzheimer's Disease Brains By Oral Delivery Of Myelin Basic Protein Bioencapsulated In Plant Cells, Neha Kohli