UCF faculty, students, and staff make new discoveries every day. This collection highlights patents obtained by the Burnett School of Biomedical Sciences since 2003.

A listing of all UCF patents, can be found here.

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Patents from 2015

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Methods and Compositions Comprising a C-Terminal Bax Peptide (US), Annette Khaled, Rebecca Boohaker, Michael Lee, and J. Manuel Perez Figueroa

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MCPIP as wound therapy, Pappachan Kolattukudy and Jianli Niu

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Vigor enhancement via administration of pyrimidine derivatives (CA), Kiminobu Sugaya and Angel Alvarez

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Methods and products for biasing cellular development, Kiminobu Sugaya, Angel Alvarez, and Amelia Marutle

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A method of biasing implanted human neural stem cells away from differentiation into glial cells by (+)phenserine to modulate the concentration of soluble ßapp in tissue or csf, Kiminobu Sugaya, Young-Don Kwak, and Amelia Marutle

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Use of modified pyrimidine compounds to promote stem cell migration and proliferation (CON DIV), Kiminobu Sugaya and Tingyu Qu

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Systems and methods of camera-based fingertip tracking (CIP), Kiminobu Sugaya and Andrew Sugaya

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Inhibitors of Stat3 (US), James Turkson and Andrew Hamilton

Patents from 2014

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Co-targeting of aurora a kinase and lim kinase 1 for cancer therapy, Ratna Chakrabarti

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Methods and compositions for inhibiting the proliferation of cancer cells (DIV), Ratna Chakrabarti

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Methods and products for reawakening retrocyclins, Alexander Cole

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MCPIP as wound therapy, Pappachan Kolattukudy and Jianli Niu

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Methods and materials for increasing potency of cells (CON 1), Kiminobu Sugaya and Angel Alvarez

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Stem cell banking system, Kiminobu Sugaya and Angel Alvarez

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System for manipulation, modification and editing of images via remote device (US-CIP), Kiminobu Sugaya, Balaji Gandhi, and Srikanth Yellanki

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Compositions for treating or delaying the onset of hair loss (US), Kiminobu Sugaya and Stephanie Merchant

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Drug composition cytotoxic for pancreatic cancer cells (US), James Turkson

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Compounds that suppress cancer cells and exhibit antitumor activity, James Turkson and Patrick Gunning

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Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of stat proteins (US), James Turkson and Patrick Gunning

Patents from 2013

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Methods and compositions for inhibiting the proliferation of cancer cells (CON), Ratna Chakrabarti

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PNMT as a novel marker for progenitor cells, Steven Ebert and Karl Pfeifer

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In vitro model of latent mycobacterial infection, Pappachan Kolattukudy, Jaiyanth Daniel, Chirajyoti Deb, and Tatiana Sirakova

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Mesenchymal stem cells with increased developmental potency by expressing Nanog, Kiminobu Sugaya and Angel Alvarez

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Methods and products for biasing cellular development, Kiminobu Sugaya, Angel Alvarez, and Amelia Marutle

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Method of promoting apoptosis of glioblastoma tumor cells, Kiminobu Sugaya, Angel Alvarez, and Stacey Mount

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Method of inhibiting AB-type bacterial toxins and treatment for associated diseases, Michael Taylor and Kenneth Teter

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Compounds that suppress cancer cells and exhibit antitumor activity (US), James Turkson and Patrick Gunning

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STAT3 inhibitor having anti-cancer activity and associated methods (EP), James Turkson, Andrew Hamilton, Richard Jove, and Said Sebti

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STAT3 inhibitor having anti-cancer activity and methods (US), James Turkson, Andrew Hamilton, Richard Jove, and Said Sebti

Patents from 2012

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In vitro model of latent mycobacterial infection (DIV I), Pappachan Kolattukudy, Jaiyanth Daniel, Chirajyoti Deb, and Tatiana Sirakova

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In vitro model of latent mycobacterial infection (DIV II), Pappachan Kolattukudy, Jaiyanth Daniel, Chirajyoti Deb, and Tatiana Sirakova

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Systems and methods of camera-based fingertip tracking, Andrew Sugaya

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Methods for increasing potency of adult mesenchymal stem cells, Kiminobu Sugaya and Angel Alvarez

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Methods for modifying stem cell characteristics, Kiminobu Sugaya and Angel Alvarez

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Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof, Kiminobu Sugaya, Christopher Brannen, Xiajing Dong, Hojoong Kim, Jose Pulido, Tingyu Qu, and Ankur Vaghani

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Tissue substitutes comprising stem cells and reduced ceria (DIV), Kiminobu Sugaya, Petya Georgiva, Stephanie Merchant, Sudipta Seal, and Manny Vrotsos

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Use of modified pyrimidine compounds to promote stem cell migration and proliferation (CON DIV), Kiminobu Sugaya and Tingyu Qu

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Methods and compounds for inhibition of cell death, Antonis Zervos

Patents from 2011

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Expression of protective antigens in transgenic chloroplasts and the production of improved vaccines (EP), Henry Daniell

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Plastid transformation vectors for expressing proinsulin fused to the cholera toxin B-subunit in plants (EP DIV), Henry Daniell

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Targeting of long chain triacylglycerol hydrolase gene for tuberculosis treatment (CON), Pappachan Kolattukudy, Jaiyanth Daniel, and Chirajyoti Deb

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In Vitro Model of Latent Mycobacterial Infection, Pappachan Kolattukudy, Jaiyanth Daniel, Chirajyoti Deb, and Tatiana Sirakova

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Targeting of triacylglycerol synthase gene for tuberculosis treatment (CON), Pappachan Kolattukudy, Jaiyanth Daniel, Vinod Dubey, and Tatiana Sirakova

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Targeting of MKRNI for identifying cancer treatment agents, Mark Muller, In Chung, Mi Kang, Jun Kim, Tae Lee, Sue Oh, and Sun Park

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User accessible tissue sample image database system and method, Kiminobu Sugaya

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Methods and products for biasing cellular development, Kiminobu Sugaya, Angel Alvarez, and Amelia Marutle

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Tissue substitutes comprising stem cells and reduced ceria, Kiminobu Sugaya, Petya Georgieva, Stephanie Merchant, Sudipta Seal, and Manny Vrotsos

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Small molecule inhibitors of stat3 with anti-tumor activity, James Turkson, Benjamin Greedy, Wayne Guida, Harshani Lawerance, Nicholas Lawrence, Said Sebti, and Man Lun Yip

Patents from 2010

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Inhibitors of prostasin, Xinqing Chai and Limei Chen

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Marker free transgenic plants: engineering the chloroplast genome without the use of antibiotic selection, Henry Daniell

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Universal chloroplast integration and expression vectors, transformed plants and products thereof (CON), Henry Daniell

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Expression of human serum albumin insulin in plastids (CIP2), Henry Daniell, Myung OK Byung, and Seung-Bum Lee

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Plastid genetic engineering via somatic embryogenisis, Henry Daniell, Shashi Kumar, and Shashi Kumar

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Use of modified pyrimidine compounds to promote stem cell migration and proliferation (UIC-A), Kiminobu Sugaya and Tingyu Qu

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Methods and compounds for inhibition of cell death, Antonis Zervos

Patents from 2009

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Targeting of long chain triacylglycerol hydrolase gene for tuberculosis treatment, Pappachan Kolattukudy, Jaiyanth Daniel, and Chirajyoti Deb

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Targeting of triacylglycerol synthase gene for tuberculosis treatment, Pappachan Kolattukudy, Jaiyanth Daniel, Vinod Dubey, and Tatiana Sirakova

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Protocol for detection of mycobacterium paratuberculosis in crohn's disease patients, Saleh Naser

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Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof, Kiminobu Sugaya, Christopher Brannen, Xiajing Dong, Hojoong Kim, Jose Pulido, Tingyu Qu, and Ankur Vaghani

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Mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof, Kiminobu Sugaya, Jose Pulido, and Tingyu Qu

Patents from 2008

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Expression of protective antigens in transgenic chloroplasts (US), Henry Daniell

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Genetic engineering of cotton to increase fiber strength, water absorption and dye binding, Henry Daniell

Patents from 2007

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Tobacco chloroplast transformation vectors comprising a multi-gene operon encoding a biopharmaceutical protein and a chaperonin (US), Henry Daniell and William Moar

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Method and compound for inhibition of cell death, Antonis Zervos

Patents from 2006

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Universal chloroplast integration and expression vectors, transformed plants and products thereof, Henry Daniell

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Genetic engineering of plant chloroplasts, Henry Daniell and Bruce McFadden

Patents from 2005

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Method of identifying and treating invasive carcinomas (CIP), Xinqing Chai, Julie Chao, Lee Chao, and Limei Chen

Patents from 2004

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Method of identifying and treating invasive carcinomas (DIV.A), Xinqing Chai, Julie Chao, Lee Chao, and Limei Chen

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Method of identifying and treating invasive carcinomas (DIV.B), Xinqing Chai, Julie Chao, Lee Chao, and Limei Chen

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Genetic engineering of plant chloroplasts, Henry Daniell and Bruce McFadden

Patents from 2003

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Method of identifying and treating invasive carcinomas, Xinqing Chai, Julie Chao, Lee Chao, and Limei Chen

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Genetic engineering of plant chloroplasts, Henry Daniell and Bruce McFadden

Patents from 1999

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Genetic engineering of plant chloroplasts, Henry Daniell and Bruce McFadden

Patents from 1997

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Genetic engineering of plant chloroplasts, Henry Daniell and Bruce McFadden