This collection contains Honors in the Major theses completed in Medicine.
Theses from 2020
The Effect of Using CRISPR/Cas9 Treatment to Delete the Myostatin Protein In Vivo and In Vitro, Marco Cardone
Comparison of Low Carbohydrate Diets on Renal and Glucose Function in Subjects with Type 2 Diabetes: A Systematic Review and Meta-analysis, Garrett A. Couch
Detection of Point Mutations Conferring Gentamicin Resistance in Escherichia coli using a Split-G4 Probe, Michael J. Greenberg
The Effect of a Senolytic Drug on Messenger RNA and Micro RNA Expression in Perigonadal Adipose Tissue of Young and Old Mice, Catalina Hernandez
Effects of Maternal Thyroid Hypofunction on Fetal Brain Development During Pregnancy: Possible Links to Autism Spectrum Disorder, Caroline R. Hobson
Isoform-Specific Expression of Adenylate Cyclase in Cardiac Development, Lauren A. Houchin
Understanding Medical Error in Surgical Stapler Use: A Philosophical and Scientific Analysis, Jacob E. Howard
Determining the Advantageous Acute Migraine Treatment: Rimegepant and Lasmiditan Review of Literature, Tiffany A. Johnson
Variations in Diet Quality Among Undergraduate Students, William Johnson
Investigating Aggression in Huntington Disease, Chloe E. LaRochelle
Investigating the Effect of Ethanol on Wnt7a and its Potential Implications in Fetal Alcohol Spectrum Disorder, Erika Lytle
The Effects of Roundup on the Life History, Stress Response, and Immune Function of the Yellow Fever Mosquito, Aedes aegypti, Lindsay E. Martin
Retrograde Labelling and Visualization of the Intrinsic Autonomic Ganglia of the Rat Liver, Kennan J. Negrete
Left Ventricular Strains during Late Filling in a Preclinical Model, Saar Peles
Nanopore-Based Metagenomic Comparison of Airway Colonizers Between Cystic Fibrosis Patients and Healthy Individuals, Anita Samadabadi
Identification and Validation of Novel Antimalarials Targeting Plasmodium Aurora Kinases, Justin T. Shaw
Regulation of the EGFR Epigenetic Landscape in Glioblastoma Multiforme, Anishaa Sivakumar
Evalutation of Human Platelet Lysate in NK Cell Culture, Elizabeth Williamson
Theses from 2019
The Analysis of the Impact of Trisomy 21 on Brain Morphometry in Humans, Yaser Ahmad
Discovery and Characterization of Antimalarials Targeting Plasmodium Falciparum Protein Kinases, Alya Barq
The Effects of Matrix Metalloproteinase-9 on CX3CL1 Shedding and Axon Retraction, Lauren A. Dobrie
Elucidating the Role of Oxygen and Biotype in the Environmental Persistence of Vibrio Cholerae, Amy M. Freiberg
Isolation of Characterization of an Endemic Population of Vibrio Cholerae in the Florida Indian River Lagoon, Carolina Ganan
An Exploration of Public Misconceptions of Municipal Water Fluoridation Relating to Oral and Public Health, Thomas A. Hawkins
Studies on the Potential Regulation of USP30 by Omi/HtrA2 Protease, Sunmi Jin
Exploring Galvanic Replacement as a Method to Engineer Peroxidase-mimics Nanoparticles, Kuryn T. MaGloire
Evaluating Lactobacillus Acidophilus as a Model Organism for Co-Culture Cancer Studies, Samuel A. Mikhail
Development of Luminescent Tools for Use in the Study of Mycobacterium tuberculosis, Krista A. Moore
The Presence of Pain Related Cytokines and Chemokines in Schwannomas and Their Potential Association with Chronic Pain in Schwannomatosis, Jackson D. Nagamoto
Micromanipulation and Genetic Analysis of Individual Sperm Cells for Sexual Assault Investigations, Amanda Penn
Proposed Biomedical Applications of Zirconium-Based Metal-Organic Frameworks as Drug Delivery Systems, Ariel Margaret Perry-Mills
Overview of Direct Thrombin Inhibitors for use in Staphylococcus Aereus Infections, Joseph C. Risler
The Role of Activin A Signaling in Gastric Reflux-Related Diseases and the Progression to Esophageal Adenocarcinoma, Cedric J. Roudebush
Determining the Potential Cleavage of Human Amyloid Beta Fibril Aggregations by the Human Matriptase Serine Protease Domain, Jonathan D. Ruiz
The Envelope Stress Response in Sedimentation-Resistant Escherichia Coli, Neel K. Shah
Role of T-Bet in Production of Immunoglobulin Isotypes in an Influenza Setting, David Sidhom
Application and Comparison of Active Learning Implementation Methods in Biochemistry Education, Dylan Thibaut
A Meta-Analysis of Neuromyelitis Optica Epidemiology in Latin American Nations, Brittany M. Zengotita
Theses from 2018
Can NoX1 Activity Initiate Parkinson's-Like Pathology in an Enteroendocrine Cell Line?, Evan Adler
Characterization of Novel Antimalarials From Compounds Inspired By Natural Products Using Principal Component Analysis (PCA), Zarina Marie G. Balde
Investigation of the Effects of Cobimetinib on Neurofibromatosis Type 2 Model Schwannoma Cells, Konstantin Brnjos
Systematic Review and Meta-Analysis: Tuberculosis, TNFα Inhibitors, and Crohn's Disease, Brent L. Cao
A Case-Study of the African Leopard (Panthera Pardus Pardus) Population on the Nambiti Private Game Reserve, Erica Castaneda
The Effect of Mismatch Primers on the Efficiency of Amplification in Quantitative Polymerase Chain Reactions, Molly C. Dawkins
Studies of Norspermidine Uptake in Drosophila Suggest the Existence of Multiple Polyamine Transport Pathways, Michael Dieffenbach
Studies on E2 Conjugation Enzyme Partners of Mulan E3 Ubiquitin Ligase, Rebekah J. Fitzpatrick
Reducing the Rate of Misdiagnosis of Postural Orthostatic Tachycardia Syndrome, Isabelle C. Gill
Investigating the Role of the Gut Microbiome in Huntington Disease, Casey G. Hart
Targeted Delivery of a Therapeutic Protein for the Treatment of Alzheimer's Disease, Heather Holman
Bacteria That Resist Centrifugal Force, Nickolas Kessler
Investigation of Aminoglycoside Induced Nanoparticle Self-Assemblies, Michael Leong
Effects of Dietary Factors on the Incidence and Progression of Non-Alcoholic Fatty Liver Disease, Spencer L. Lessans
Investigating the Role of the Caspase-6 Cleavage Fragment of Mutant Huntingtin in Huntington Disease Pathogenesis, Jourdan A. McKinnis
An Exploration into the Psychotic Symptoms Associated with Schizophrenia and Major Depressive Disorder, Kyndester I. Michael-Samaroo
The Effects of Site-Directed Mutagenesis on Hemerythrin-like Protein Rv2633c, Kelly M. Rosch
Development of Methods to Modulate Natural Killer Cells, Kari A. Shaver
Parasympathetic Nerve Derived Exosomes Inhibit Hyperglycemia Induced Apoptosis in Cardiomyoblast Cells, Reetish K. Singla
Theses from 2017
The Use of Hands-on Educational Pedagogy in A Standardized Science Curriculum, Sarah Alam
Analysis of the Prevention of Biocorrosion Caused by Desulfovibrio alaskensis G20, Michael Boring
The Role of Frabin (FGD4) in Aggressive Prostate Cancer, Alexia M. Bossan
The Role of Breastfeeding in Mother-to-Child Transmission of HIV/AIDS: A Comparative Case Study of Three Countries, Anjali Cherukuri
Testing Mice at Risk of Pancreatic Cancer for Altered Protein Pathways Found in Diabetes, Henley Cheung
Validating Drug Targets through Inhibition of Protein-Protein Interactions in Mycobacterium Tuberculosis, Erin C. Driscoll
Alpha-Synuclein: Insight into the Hallmark of Parkinson's Disease as a Target for Quantitative Molecular Diagnostics and Therapeutics, Baggio A. Evangelista
Micro-Spectroscopy of Bio-Assemblies at the Single Cell Level, Jeslin Kera
Activation and Expansion of Natural Killer Cells for Cancer Immunotherapy With EX21 Exosomes, Sara Khederzadeh
The Response of Satellite Glial Cells to P2X7 Receptor Activation, Christina D. Kursewicz
Characterizing the Function of the N-Terminal Domain of Omi/HtrA2, Christine Nguyen
The Effect of K562-IL21-2 Plasma Membrane Particles on the Proliferation of Natural Killer Cells to Fight Cancer, Michelle Prophete
To Evaluate the Function of the Oxytocin Receptor in the Context of Ovarian Cancer Cell Microenvironment to Determine if Oxytocin can Induce an Anti-Inflammatory Response, Benjamin I. Schachner
Structural Transition During Fibrillogenesis of Amyloid β Peptide, George Sidrak
Identifying the Effects of a Human Dynein Mutation on GFP-Rab7 Axonal Transport in Embryonic Mouse Neurons, Natalie E. Wilson
Theses from 2016
Characterization of Hemerythrin-like Protein Rv2633c, Michelle D. Cherne
Microenvironment Changes in the Pancreatic Stroma Induced by Inflammation, Kathryn Cline
Identification and Characterization of Interactors of Plasmodium falciparum PfPK6, An Atypical Protein Kinase, Andi J. Cummins
The Role of the Intermembrane Domain of Mulan in Mitophagy and Cell Death, Jared M. Herbert
Identification of the Effects of Diabetes Mellitus on the Brain, Tryphina A. Mikhail
Aptameric Sensors: In Vitro Selection of DNA that Binds Bromocresol Purple, Derek B. Miller
Screening for Anticancer Agents to Inhibit Mitotic Kinases and Proliferation of Metastatic Prostate Cancer Cells, Khoa Nguyen
The Effect of Caffeine on Migraine Headaches, Deborah Shimshoni
Cardiac Consequences of Selective Adrenergic Cell Ablation in Mice, Lahari Tumuluri
Theses/Dissertations from 2015
Effects of GHRKO Visceral Fat Transplant on Insulin Signaling, Mohammed Bennis
Identification of the Domain(s) in Protein Disulfide Isomerase Required for Binding and Disassembly of the Cholera Holotoxin, Laura Herndon
Polyamine Transport Inhibitor Effects on Pancreatic Cancer Proliferation Cells in Vivo, Frederick Hogan
Characterizing the Onset and Progression of Charcot-Marie-Tooth Neuropathy in H304R Mutant Mice, Aaron Ledray
The Relationship Between Patient Education and Adherence to Antibiotic Regimens: Exploring Profiles of Adherent Groups, Morgan McSweeney
Homophobia and HIV Transmission: A Six-Country Comparative Analysis, Tiernan Middleton
The Effect of Bacterial Vaginosis Associated Bacteria on Epithelial Factors Mediating HIV Transmission, April Nguyen
Analysis of the Pathomechanism of Migraines with a Focus on Current Treatment Plans and the Role of the Neuropeptide CGRP, Marvi Qureshi
Detection and Characterization of Pathogenic Mycobacteria Using Binary Deoxyribozymes, Bradley Rosenkrantz
Hepatic Lipase Regulates LipoProtein Trafficking in Hepatocytes, Simeon Thibeaux
Development of a Fluorescent Drug Screening Platform for Inhibitors of Mycobacterium Tuberculosis Protein-Protein Interactions, Zina Versfeld